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Comparative Efficacy Of Prazequantel, Niclosamide And Pumpkin Seeds Against Dipylidium Caninum In Dogs

by Ayesha Arif (2015-VA-22) | Dr. Asim Khalid Mahmood | Dr. Uzma Farid Durrani.

Material type: book Book Publisher: 2017Dissertation note: Dypilidium caninum is a hermaphrodite Cestode (flatworm) consisting of a scolex, neck region and repeating segments and lacking mouth, intestine and body cavity. It has an indirect life cycle. The adult form of the tapeworm is acquired by definitive host through the ingestion of intermediate host which contains the larval metacestode stage. The major aftermath of such infections is the shedding of eggs and proglottids. It is a serious economic and zoonotic health threat. Life-threatening disease in humans, dogs and cats can be resulted by the presence of the of tapeworms immature (metacestode) stages occurring in various tissues. The dogs clinically suspected for Dipylidium caninum and dogs having flea infestation were subjected to fecal analysis/EPG for D. caninum. Thirty dogs positive for D. caninum were divided randomly into 3 groups of 10 i.e. A, B and C. The dogs in group A were treated with praziquantel at the dose rate of 5 mg/kg orally while the animal in group B were given niclosmiode at the dose rate of 100 mg/kg per oral. The members in the group C were given pumpkin seeds powder at the dose rate of 5 gram orally. The fecal samples from dogs in each group were collected at day 0 (pretreatment) and then at day 7, 14 and 21 (post treatment). Standard fecal flotation technique was performed for identification of Dipylidium caninum eggs using saturated salt solution. McMaster counting chamber was used for the counting of eggs. The study results were analyzed using one way ANOVA on SPSS version 17.0. The results showed that in a post-treatment sampling of group A, the EPG count was significantly Summary 37 reduced. Group B smplings also showed a good reduction in EPG but with the second dose whereas group C results were unsatisfactory. On the basis of the results of this study it was concluded that Praziquantel is much more effective against Dypilidium caninum as compared to Niclosamide and pumpkin seeds, but high cost and no availability in Pakistan makes it difficult to be effectively used against Dypilidium caninum while niclosaamide is easily available and low in price. Niclosamide is effective against Dypilidium caninum but not up to the extent of praziquantel. Pumpkin seeds have poor effect on Dypilidium caninum Availability: Items available for loan: UVAS Library [Call number: 2856-T] (1).

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2.
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Comparative Efficacy Of Prazequantel, Niclosamide And Pumpkin Seeds Against Dipylidium Caninum In Dogs

by Ayesha Arif (2015-VA-22) | Dr. Asim Khalid Mahmood | Dr. Uzma Farid Durrani | Prof. Dr. Waseem Shehzad.

Material type: book Book Publisher: 2017Dissertation note: Dypilidium caninum is a hermaphrodite Cestode (flatworm) consisting of a scolex, neck region and repeating segments and lacking mouth, intestine and body cavity. It has an indirect life cycle. The adult form of the tapeworm is acquired by definitive host through the ingestion of intermediate host which contains the larval metacestode stage. The major aftermath of such infections is the shedding of eggs and proglottids. It is a serious economic and zoonotic health threat. Life-threatening disease in humans, dogs and cats can be resulted by the presence of the of tapeworms immature (metacestode) stages occurring in various tissues. The dogs clinically suspected for Dipylidium caninum and dogs having flea infestation were subjected to fecal analysis/EPG for D. caninum. Thirty dogs positive for D. caninum were divided randomly into 3 groups of 10 i.e. A, B and C. The dogs in group A were treated with praziquantel at the dose rate of 5 mg/kg orally while the animal in group B were given niclosmiode at the dose rate of 100 mg/kg per oral. The members in the group C were given pumpkin seeds powder at the dose rate of 5 gram orally. The fecal samples from dogs in each group were collected at day 0 (pretreatment) and then at day 7, 14 and 21 (post treatment). Standard fecal flotation technique was performed for identification of Dipylidium caninum eggs using saturated salt solution. McMaster counting chamber was used for the counting of eggs. The study results were analyzed using one way ANOVA on SPSS version 17.0. The results showed that in a post-treatment sampling of group A, the EPG count was significantly Summary 37 reduced. Group B smplings also showed a good reduction in EPG but with the second dose whereas group C results were unsatisfactory. On the basis of the results of this study it was concluded that Praziquantel is much more effective against Dypilidium caninum as compared to Niclosamide and pumpkin seeds, but high cost and no availability in Pakistan makes it difficult to be effectively used against Dypilidium caninum while niclosaamide is easily available and low in price. Niclosamide is effective against Dypilidium caninum but not up to the extent of praziquantel. Pumpkin seeds have poor effect on Dypilidium caninum Availability: No items available

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Study On Whole Blood Xenotransfusion In Domestic Cats

by Ihtesham Yousaf (2015-VA-17) | Dr. Uzma Farid Durrani | Dr. Asim Khalid Mahmood | Dr. Raheela Akhtar.

Material type: book Book; Literary form: not fiction Publisher: 2017Dissertation note: Cat is the most domesticated pet all over the world. However, there are numerous clinical emergency situations of cats which require immediate blood transfusion but due to limited availability of cat blood donors;it becomes challenging for practitioners to save the patient’s life.In case ofdire need of blood transfusion when feline blood is unavailable; xenotransfusion with canine blood can be attempted. Xenotransfusionrefers to thetransfusion of blood from one species to another species. The present study was conducted on 20 rescue domestic cats divided into two groups: i.e. Experimental group and control group, each with 10 cats. In experimental group blood of 10 clinically healthy German Shepherddogs (donor) was transfused to10 adult rescue domestic cats suffering severe accidental blood loss. Control group received 0.9% normal saline infusion. Pre and post blood transfusion hematological evaluation was done for each recipient cat on days 0, 1, 3 and 7. Parameters for hematological evaluation included complete blood count, CRT, SpO2and arterial blood pressure.Obtained data was statistically analyzed by repeated measures of analysis of variance (ANOVA) within control and experimental group while between groups data was statistically analyzed using independent sample t-test.On the basis of findings of this study xeno-transfusion is proved to be a safe and effective life saving technique for cats suffering critical blood loss. Availability: Items available for loan: UVAS Library [Call number: 2944-T] (1).

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Comparative Efficacy Of Fipronil And Ivermectin Against Knemidocoptes In Budgerigars

by Serug Akhtar (2015-VA-1069) | Dr. Uzma Farid Durrani | Dr. Asim Khalid Mahmood | Dr. Haroon Akbar.

Material type: book Book; Literary form: not fiction Publisher: 2017Dissertation note: Knemidocoptes pilae causes scaly face condition in budgerigars. Present study was conducted in different K. pilae suspected cases of budgerigars at Pet Centre, University of Veterinary and Animal Sciences Lahore. After the confirmation of knemidocoptes through skin scraping the birds were treated in 2 groups (10 birds each group), on group was topically treated with Fipronil and the other group was topically treated with Ivermectin. Fipronil was applied on neck region on days 0,7,14 and the birds were examined for mite infestation on day 0,7,14 and 21. Similarly the ivermectin was also applied topically on neck region on day 0,7 and 14. Where infestation was reconfirmed by skin scraping on day 0, 7, 14 and 21. The group treated with fipronil showed generalized clinical improvement in health (Body weight, body itch, feed intake, activity and skin lesion) after day 14 whereas all the skin lesions disappeared by day 21. Ivermectin the birds started showing improvement in health (Body weight, body itch, feed intake, activity and skin lesion) on day 7 post treatment and all the skin lesion healed by day 21. On the basis of findings of this study it is conducted that bot ivermectin and fipronil are effective against K. pilae however ivermectin induced recovery is fast as compared to fipronil. Availability: Items available for loan: UVAS Library [Call number: 2955-T] (1).

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